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full-length synthetic human or rat αcgrp 1-37 peptide  (Bachem)

 
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    Structured Review

    Bachem full-length synthetic human or rat αcgrp 1-37 peptide
    a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human <t>αCGRP</t> peptide immunogen, p4796kb, and the <t>rat</t> <t>αCGRP</t> peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.
    Full Length Synthetic Human Or Rat αcgrp 1 37 Peptide, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+peptides+%CE%B1cgrp(1-37)/synthetic+cgrp++rat+sequence++cgrp+type+i++cgrp+%CE%B1+/pmc12041250-99-18-21
    Average 90 stars, based on 1 article reviews
    full-length synthetic human or rat αcgrp 1-37 peptide - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Preclinical characterization of an active immunotherapy targeting calcitonin gene-related peptide"

    Article Title: Preclinical characterization of an active immunotherapy targeting calcitonin gene-related peptide

    Journal: Communications Medicine

    doi: 10.1038/s43856-025-00870-2

    a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human αCGRP peptide immunogen, p4796kb, and the rat αCGRP peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.
    Figure Legend Snippet: a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human αCGRP peptide immunogen, p4796kb, and the rat αCGRP peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.

    Techniques Used: Sequencing, Injection

    Related Articles

    other:

    Article Title: Characterization of the Two-Domain Peptide Binding Mechanism of the Human CGRP Receptor for CGRP and the Ultrahigh Affinity ssCGRP Variant
    Article Snippet: Synthetic human peptides αCGRP(1-37), αCGRP(8-37), and AM(13-52) were purchased from Bachem (Bubendorf, Switzerland).

    Article Title: Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin 2 G protein–coupled receptor
    Article Snippet: Synthetic human peptides αCGRP(1–37), AM(13–52), and AM2/IMD(1–47) were purchased from Bachem.

    Article Title: Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin 2 G protein-coupled receptor
    Article Snippet: Synthetic human peptides αCGRP(1-37), AM(13-52), and AM2/IMD(1-47) were purchased from Bachem (Bubendorf, Switzerland).



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    full-length synthetic human or rat αcgrp 1-37 peptide  (Bachem)
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    Bachem full-length synthetic human or rat αcgrp 1-37 peptide
    a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human <t>αCGRP</t> peptide immunogen, p4796kb, and the <t>rat</t> <t>αCGRP</t> peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.
    Full Length Synthetic Human Or Rat αcgrp 1 37 Peptide, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    human peptides αcgrp(1-37)  (Bachem)
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    Bachem human peptides αcgrp(1-37)
    a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human <t>αCGRP</t> peptide immunogen, p4796kb, and the <t>rat</t> <t>αCGRP</t> peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.
    Human Peptides αcgrp(1 37), supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+peptides+%CE%B1cgrp(1-37)/human+%CE%B1cgrp/pmc12004451-57-0-10
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    Image Search Results


    a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human αCGRP peptide immunogen, p4796kb, and the rat αCGRP peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.

    Journal: Communications Medicine

    Article Title: Preclinical characterization of an active immunotherapy targeting calcitonin gene-related peptide

    doi: 10.1038/s43856-025-00870-2

    Figure Lengend Snippet: a Sequence alignment of the 37mer signaling peptide, CGRP. Conserved residues represented by *. Red box indicates the targeting peptide sequence (B cell epitope) of the human αCGRP peptide immunogen, p4796kb, and the rat αCGRP peptide immunogen, p5830kb. Anti-CGRP antibody titers over time in rat ( n = 5) ( b ), guinea pig ( n = 3) ( c ), and NHP ( n = 3) ( d ). Anti-human αCGRP (K35K) ( e ) and anti-rat αCGRP (K35E) ( f ) IgG titers in sera collected post-immunization in rats injected with p4796kb or p5380kb ( n = 5 per group). g Serum concentrations (μg/mL) of anti-CGRP antibodies. Red arrowheads indicate dosing time points. Individual data points are presented on each graph.

    Article Snippet: Microtiter 96-well plates were 1st coated with 100 μL of 2 μg/mL of the full-length synthetic human or rat αCGRP 1-37 (Bachem, CA, product number 4013281) peptide at room temperature (RT) for 1 h and 4 °C overnight.

    Techniques: Sequencing, Injection